Molecule Prevents Common Cold Virus from Hijacking Human Cells

Molecule Prevents Common Cold Virus from Hijacking Human Cells

Molecule Prevents Common Cold Virus from Hijacking Human Cells

The common cold is caused by viruses with hundreds of variants, and these overwhelming numbers can hinder efforts to immunize or vaccinate ourselves against them. It targets a protein in human cells, known as N-myristoyltransferase (NMT), that viruses steal from human cells to create their protective capsid by preventing any fatty-acid attachment.

Caused by a family of viruses with hundreds of variants, it is almost impossible to treat, as no single vaccination exists against it, meaning people resort to treating the symptoms rather than the virus itself.

Any virus needs this same human protein to make new copies of itself and, as this new molecule can target NMT, it can work against the common cold. The researchers believe that it could work against other related viruses, including those responsible for polio and foot-and-mouth disease.

More news: AGENTS OF SHIELD Moved to Mid-Season With Fewer Episodes

Lead researcher Professor Ed Tate, from the Department of Chemistry at Imperial, said: "The common cold is an inconvenience for most of us, but can cause serious complications in people with conditions like asthma and COPD". If successful the cold cure could be available within five years. In this study, the researchers found no side effect to human cells.

It's early days for the research, so far only tested out in a petri-dish, but the scientists on the project are hoping to swiftly move to animal and then human trials.

"While this study was conducted entirely in vitro, i.e using cells to model rhinovirus infection in the laboratory, it shows great promise in terms of eventually developing a drug treatment to combat the effects of this virus in patients". But what if there were one way to block the ability of all cold viruses from replicating-thereby fending off the sneezing, sore throat and general misery that they cause? The scientists found they were able to block replication of several strains of the virus without human cells being affected.

More news: Soros Foundation moves from Budapest to Berlin

By targeting the human protein and not the virus itself, the molecule makes the emergence of resistant viruses highly unlikely.

The molecule was initially discovered when searching for a way to take on malaria parasites.

A 1913 poster about the common cold.

More news: Xiaomi Redmi S2 To Launch In India On June 7th

Recommended News

  • Low pens new Germany deal drops 27-man provisional WC squad

    Low pens new Germany deal drops 27-man provisional WC squad

    Germany are in Group F with Mexico, Sweden and South Korea, and play their first match on Sunday, 17 June. However, he missed out on playing in the 2014 World Cup due to an injury-hit season.
    The clock is ticking, EU warns Britain of poor Brexit progress

    The clock is ticking, EU warns Britain of poor Brexit progress

    The document is due to be formally unveiled at an event later this month where Immigration Minister Caroline Nokes is set to give a keynote speech, the report said.
    Fox, NBC decide less is more to start the fall season

    Fox, NBC decide less is more to start the fall season

    Tim Allen will be back on TV as his sitcom Last Man Standing , which was canceled by ABC a year ago, moves to Fox's fall schedule. As the leading broadcast TV network, NBC has few positions in the fall for new shows - with only three new series.
  • European Union  expands sanctions against Russian Federation  for 'election' in Crimea - Poroshenko

    European Union expands sanctions against Russian Federation for 'election' in Crimea - Poroshenko

    Russian President Vladimir Putin inspects the road section of the road-and-rail Crimean Bridge over the Kerch Strait on March 14. Putin at the wheel of Kamaz headed the convoy of the vehicles and cargo equipment that made the first trip over the bridge.
    NASA Mars Helicopter Technology Demonstration

    NASA Mars Helicopter Technology Demonstration

    NASA considers the mission "a high-risk, high-reward project" and if it fails, it doesn't impact the rest of the rover's mission. Four years in the making, the NASA team finally decided that the autonomous helicopter can be sent to the Red Planet.
    Honor 10 details: iPhone X and Galaxy S9's features remixed

    Honor 10 details: iPhone X and Galaxy S9's features remixed

    The front of the smartphone is dominated by the 5.84 inch IPS LCD display with a 2280 x 1080 px resolution. The Honor 10 will come in 4 colors - Phantom Blue, Mirage Purple, Magic Night Black and Grey Gull.
  • Star Fox Grand Prix Coming from Retro Studios

    Star Fox Grand Prix Coming from Retro Studios

    "These sources did not confirm whether the project being worked on was this Star Fox title". Many scoff at the possible new take on the franchise.
    Mercedes restore order at top with Hamilton's win

    Mercedes restore order at top with Hamilton's win

    Mercedes now do not have any drivers under contract for 2019 as Valtteri Bottas is also in the final year of his current deal. He added: "The pressure and the passion that I have to win this championship are far greater than I've ever had it".
    Dismantling of North Korea nuclear site 'well under way', satellite images show

    Dismantling of North Korea nuclear site 'well under way', satellite images show

    In one of the first signs that Kim was willing to concede Punggye-ri, he announced last month that the site had "done its job". Observation and research facilities and ground-based guard units will also be removed, the North said.
  • You can try Mario Tennis Aces early for free

    You can try Mario Tennis Aces early for free

    Another short clip highlighted the game's single-player Adventure Mode. "Luigi's in a load of trouble" our narrator tells us. Earlier this year Nintendo announced a new Mario game for the Nintendo Switch in the form of Mario Tennis Aces .
    Gap pulls shirt with incorrect map of China from stores, issues apology

    Gap pulls shirt with incorrect map of China from stores, issues apology

    Other US companies which have issued apologies for similar incidents include Delta Air Lines and Marriott International Inc. The printed map did not include Taiwan , a self-ruled island considered Chinese territory by Beijing, the capital.

    By the Numbers: Cavs' Draft Lottery

    And after missing the playoffs by one game this season, they'll need a miracle to land the No. 1 overall pick. This year, three teams - Brooklyn, the Los Angeles Lakers and Detroit - traded away their first-round picks.

We are pleased to provide this opportunity to share information, experiences and observations about what's in the news.
Some of the comments may be reprinted elsewhere in the site or in the newspaper.
Thank you for taking the time to offer your thoughts.